Basket trials, along with umbrella trials and platform trials, are classified as master protocols which…
Canada: For Your Phase 3 Global Trial Expansion
Oncology continues to be the largest and fastest growing therapeutic area in the clinical trials market, and a market dominated by Phase 3 trials is a key trend predicted to continue into 2024.
It may take some time for new oncology study launches to get back up to pre-pandemic speed. At the same time, the fight for a cure for cancer continues to see Oncology with the most funding in private and public financings, and the most M&A related deal activity, by far in 2021.
A Region of Interest for Phase 3 Global Studies
The larger patient pool necessary for Phase 3 trials often requires a global scope, in addition to laying the path for eventual drug approval requests in more than one region. Conducting a Phase 3 oncology trial across multiple regions also allows for access to a more demographically diverse patient population and mitigates different types of enrollment barriers. Canada is a key region to achieve these objectives.
For smaller biotech companies the stakes are high for any Phase 3 trial. With limited resources and pipelines, successful execution of a global Phase 3 trial is critical as outcomes may determine the future of the compound and possibly the ultimate survival of the company itself.
Participation by Canadians in oncology clinical trials is 14%. Nearly triple the 5% participation rate in the U.S. Projections to 2036 indicate people of color will make up about one third (31% to 36%) of the total Canadian population. A diverse population combined with a universal healthcare system for all Canadian citizens offers a compelling opportunity for cutting-edge U.S. biotechs striving to ensure global trials get the right mix of participants.
In Canada cancer patients are funneled through select oncology health centers across the country and will typically receive treatment at the same center throughout the evolution of their disease (1st, 2nd line, 3rd line, etc). A factor that greatly aids in identification of possible oncology trial participants.
Canada currently ranks 5th among countries (excluding the U.S.) that contribute the greatest number of clinical trial participants globally. While the number of physicians per population has increased in Canada over the past decade, and is expected to continue to increase for the next several years.
Results Achieved with the Right Partner
Year-over-year the attributes Sponsors seek from their clinical trial outsourcing partners remains the same. Quality and reliability are the number one and number two priorities. The right partner will integrate your study plan seamlessly, bringing key mitigating actions and solutions throughout the study conduct, without adding administrative or logistic burden to your team members. This is critical at the early stage of clinical development, and even more so at the late stage when trial scope is broader, and a greater number of players are involved.
Based on the metrics achieved by Canadian oncology CRO, Scimega, biotechs developing cutting edge oncology therapies with this partner are quoted as being very impressed with where Canada stands in comparison to other regions.
Scimega guarantees Sponsors the quickest site start-up and the highest patient recruitment rate, without sacrificing premium quality data. Identification and qualification of the right Canadian sites for each study is completed within just a few weeks thanks to Scimega’s extensive network of Canadian Investigators. These Canadian sites are then activated 50% faster than the industry average, and frequently emerge among top enrollers in sponsors’ global oncology studies. This is achieved even under the current pandemic circumstances.
What Your Specialized Oncology CRO Can Do for You – Real World Evidence
Mobilizing an expert Canadian team with strong relationships with clinical sites significantly enhances study start-up and overall performance. The following real-world enrollment metrics features how Scimega’s unwavering strategic focus delivers on its commitment to Sponsor’s programs.
Your Specialized Oncology CRO – Scimega Consistently Goes Above-and-Beyond
With 25 years unparalleled Canadian oncology experience Scimega Research has an optimal operations design critical to its ability to consistently go above-and-beyond for every one of your studies. Contact us to know how Scimega and Canadian sites could contribute to your oncology program, we’ll be happy to share our latest performance metrics on similar projects!
Scimega is a Canadian niche oncology CRO that serves small to medium size biotech companies in clinical development of cutting-edge oncology therapies. We consistently deliver our services with a strategic focus on Sponsor program success with clinical trial start-up times 50% faster than the North American average, premium quality data, and trial sites that are often among top enrollers in our Sponsors’ global oncology studies.
Contributed by: Julie Martin, CEO & co-Owner